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Discoveries Interview: Professor Christian Weber on the inflammation in cardiovascular diseases

DISCOVERIES (ISSN 2359-7232), 2015, January-March


Discoveries Interview: Professor Christian Weber on the inflammation in cardiovascular diseases. Discoveries 2015, Jan-Mar; 3(1): e36. DOI: 10.15190/d.2015.02; 

Submitted: February 3rd, 2015; Revised: February 4th, 2015; Accepted: February 5th, 2015; Published: February 10th, 2015;

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Discoveries Interview: Professor Christian Weber on the inflammation in cardiovascular diseases

Professor Christian Weber studied medicine at the Ludwig Maximilians – University (LMU)  of Munich, Germany, the University Hospital Galway, Ireland and Princess Alexandra Hospital, Australia.  After receiving his medical degree in 1994, he joined the Center for Blood Research (T. Springer), Harvard Medical School for a postdoctoral research fellowship. Coming back to Germany, he was awarded as junior research group leader in Vascular Medicine at the Ludwig-Maximilians-University and later was appointed as full-time professor and head of Molecular Cardiology at the University Hospital of the RWTH Aachen. As founding Director of the Institute for Molecular Cardiovascular Research in Aachen, he became a prominent and well-known figure in cardiovascular field, launching well-funded hypothesis and opening novel visions on therapeutic strategies for cardiovascular diseases. In 2010, he was appointed as Chair in Vascular Medicine and Director of the Institute for Cardiovascular Prevention, the Ludwig - Maximilians - University of Munich, as well as Chair of the August-Lenz-Foundation. 

During his career, he published more than 400 scientific articles, with a cumulative impact factor over 3100 and more than 20 000 citation, achieving the h-index of 74. His activity was recognized and awarded by the German Society of Atherosclerosis Research (W.H. Hauss-Prize), the European Society of Cardiology (Outstanding Achievement Award 2008), the American Heart Association (ATVB Special Recognition Award) and the Netherlands Organization for Scientific Research (VICI Award). He is the Chief Editor, Editorial Board Member and/or Referee of many prestigious scientific journals, as well as the president and/or important organizer of several scientific meetings. At last, but not at least, he is an appreciated model and mentor for many ambitioned and motivated young scientists. 

Access full text of the manuscript here: 


1. Gerdes N, Winkels H, Weber C. Atheroslerosis: cell biology and lipoprotein-focus on anti-inflammatory mechanisms as therapeutic options. Curr Opin Lipidol 2013; 24: 187-189. 

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2. Weber C, Zernecke A, Libby P. The multi-facetted contribution of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol 2008; 8:802-815. 

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3. Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C.  Disrupting functional interaction between platelet chemokies inhibits atheroslerosis in hyperlipidemic mice. Nat Med 2009; 15: 97-103. 

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4. Matusik P, Guzik B, Weber C, Guzik TJ. Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice? Thromb Haemost 2012; 108: 443-456. 

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5. Silvestre-Roig C, de Winther MP, Weber C, Daemen MJ, Lutgens E, Soenlein O. Atherosclerotic plaque destabilisation: mechanisms, models, and therapeutic strategies. Circ Res 2013; 114: 214-216. 

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