DISCOVERIES (ISSN 2359-7232), 2019, July-September issue
Submitted: August 30th, 2019; Revised: September 3rd, 2019; Accepted: September 10th, 2019; Published: September 30th, 2019;
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Cardiac FGF23: a new player in myocardial infarction
David Schumacher (1,*), Alexander Schuh (2)
(1) Department of Anesthesiology, University Hospital, RWTH Aachen, Germany
(2) Department of Cardiology, Angiology and Intensive Care, University Hospital, RWTH Aachen, Germany
*Corresponding author: David Schumacher, MD, Department of Anesthesiology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany; Phone: 0049-1515-91 65615; Fax: 0049-241-80 82142; Email: dschumacher@ukaachen.de
Abstract
Fibroblast Growth Factor 23 (FGF23) is a hormone involved in phosphate metabolism. It is known that FGF23 is increased in different pathologies including chronic kidney disease, heart failure or X-linked hypophosphatemia and directly correlates with negative outcome and mortality in severe diseases. However, the role of FGF23 in cardiovascular pathologies is still under debate. This review summarizes the current knowledge about the role of FGF23 in ischemic heart diseases, such as myocardial infarction.
Access full text of the manuscript here: Full text (pdf)
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