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Peer-reviewed articles published in Discoveries

DISCOVERIES ISSN 2359–-7232; DISCOVERIES published 60 Peer-Reviewed articles.

Please CITE these articles as shown in RED.

ORIGINAL Articles

Self-assembly of Deinococcus radiodurans supports nanocell scenario of life origin

Bernadotte A, Semenova V, Musial VAM, Kasprzykowska A, Zubarev RA. Self-assembly of Deinococcus radiodurans supports nanocell scenario of life origin. Discoveries 2017, 5(1): e72. DOI: 10.15190/d.2017.2
Country of the authors Sweden
Corresp. authors' affiliationProf. Roman Zubarev, PhD, Head of the Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles väg 2, SE-17177 Stockholm, Sweden;
Funding start-up grant (to RZ)
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Unique morphological characteristics of mitochondrial subtypes in the heart: the effect of ischemia and ischaemic preconditioning

Kalkhoran SB, Munro P, Qiao F, Ong S, Hall AR, Cabrera-Fuentes H, Chakraborty B, Boisvert WA, Yellon DM, Hausenloy DJ. Unique morphological characteristics of mitochondrial subtypes in the heart: the effect of ischemia and ischemic preconditioning. Discoveries 2017, 5(1): e71 DOI: 10.15190/d.2017.1
Country of the authors UK, Singapore, Russia, USA
Corresp. authors' affiliation: Dr. Derek J Hausenloy, MD, Cardiovascular & Metabolic Diseases Program, Duke-NUS Graduate Medical School Singapore, Singapore;
Funding British Heart Foundation (grant number FS/10/039/28270), the Rosetrees Trust, and supported by the National Institute for Health Research University College London Hospitals Biomedical Research Centre (to DJH); Medical Research Council (grant number MR/J003530/1), (Duke-NUS-KPFA/2016/0010) from the Estate of Tan Sri Khoo Teck Puat, Singapore and Singapore’s Ministry of Health National Medical Research Council under its Open Fund - Young Individual Research Grant scheme (NMRC/OFYIRG/0021/2016) (to ARH). Part of the work was supported by the Russian Government Program for competitive growth of Kazan Federal University (to HCF).

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Isoelectric point region pI≈7.4 as a treasure island of abnormal proteoforms in blood

Pirmoradian M, Aarsland D, Zubarev RA. Isoelectric point region pI≈7.4 as a treasure island of abnormal proteoforms in blood. Discoveries 2016, Jul-Sep; 4(4): e67 DOI: 10.15190/d.2016.14
Country of the authors Sweden
Corresp. authors' affiliation: Prof. Roman Zubarev, PhD, Head of the Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Scheeles väg 2, SE-17177 Stockholm, Sweden; 
Funding Swedish Research council (grant 2011-3699), VINNOVA Foundation (grants within the EuroStar 2010 and 2015 Programs), and the Knut and Alice Wallenberg Foundation (grant KAW 2010.0022) (to RZ).

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Advanced modular automated calculation of the morpho-histological parameters in myocardial infarction

Pop-Fele L, Curaj A, Jovanovici M, Jonas SM, Moellmann J, Ghertescu D, Novac OC, Rusu M. Liehn EA. Advanced modular automated calculation of the morpho-histological parameters. Discoveries 2016, Jul-Sep; 4(3): e66. DOI: 10.15190/d.2016.13
Country of the authors Germany and Romania
Corresp. authors' affiliationDr. Elisa Liehn, MD, PhD, Institute for Molecular Cardiovascular Research (IMCAR), University Hospital RWTH Aachen, Germany; 
Funding Interdisciplinary Center for Clinical Research IZKF Aachen (to EAL)

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Biodistribution and scintigraphic evaluation of 99mTc-Mannan complex

Sanguri S, Gupta D, Singh T, Singh AK. Biodistribution and scintigraphic evaluation of 99mTc-Mannan complex. Discoveries 2016, Jul-Sep; 4(3): e65. DOI: 10.15190/d.2016.12

Country of the authors India
Corresp. authors' affiliationDr. Damodar Gupta, PhD, Division of Metabolic Cell Signaling Research, INMAS, Defence Research and Development Organization (DRDO), Delhi, India
Funding DRDO, Ministry of Defence, India (to DG) and award fellowship from CSIR (to SS)

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Validation of commercially available ELISAs for the detection of circulating sclerostin in hemodialysis patients

Mause SF, Deck A, Hennies M, Kaesler N, Evenepoel P, Janssen U, Brandenburg VM. Validation of commercially available ELISAs for the detection of circulating sclerostin in hemodialysis patients. Discoveries 2016, January-March; 4(1): e55. DOI: 10.15190/d.2016.2

Country of the authors Germany, Switzerland, Belgium and USA
Corresp. authors' affiliationDr. Mause, MD, Department of Cardiology, Pauwelsstraße 30, D‐52074 Aachen, University Hospital RWTH Aachen, Germany; # - equal contribution
Funding NIH (R01HL081863 to WAB).
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Studies on radiation sensitization efficacy by silymarin in colon carcinoma cells

Lal M, Gupta D. Studies on radiation sensitization efficacy by silymarin in colon carcinoma cells. Discoveries 2016, January-March; 4(1): e56. DOI: 10.15190/d.2016.3
Country of the authors India 
Corresp. authors' affiliation: Dr. Gupta, PhD, Division of Metabolic cell signaling and research, Institute of Nuclear Medicine & Allied Sciences, DRDO, Brig SK Mazumdar Marg, Timarpur, Delhi, India
Funding: grant from University Grants Commission (UGC) of India, a statutory body set up by the Indian Union government (to DG)

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Blockade of CCR3 retains the neutrophils, preserving their survival during healing after myocardial infarction

Curaj A, Staudt M, Fatu R, Kraaijeveld AO, Jankowski J, Biessen EAL, Liehn EA. Blockade of CCR3 retains the neutrophils, preserving their survival during healing after myocardial infarction. Discoveries 2015, Jul-Sep; 3: e45. DOI: 10.15190/d.2015.37
ARTICLE (pdf)  Abstract, Citation & References  Citations: 1    
Country of the authors Germany, Romania, Netherlands 
Corresp. author's affiliation: Prof.  Elisa Liehn, MD, PhD, Institute for Molecular Cardiovascular Research, University Hospital Aachen, Germany.
Funding: Interdisciplinary Center for Clinical Research IZKF Aachen (to EAL)

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Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker

Kovach AE, Nucera C, Lam QT, Nguyen A, Dias-Santagata D, Sadow PM. Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker. Discoveries 2015, 3(2): e40. DOI: 10.15190/d.2015.32
ARTICLE (pdf)  Abstract, Citation & References  Supplementary Data (pdf)  Citations: 1  PubMed    
Country of the authors USA
Corresp. author's affiliation: Prof. Sadow, MD, PhD, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Funding grants from NCI/NIH (1R21CA165039-01A1 and 1R01CA181183-01A1), the American Thyroid Association, ThyCa:Thyroid Cancer Survivors Association Inc.Guido Berlucchi “Young Investigator” research award and BIDMC CAO (Chief Academic Officer) Grants (to CN); departmental funds, Department of Pathology, Massachusetts General Hospital (to PMS)

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Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice

Kubo N, McCurdy S, Boisvert WA. Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice. Discoveries 2015, 3(1): e37. DOI: 10.15190/d.2015.29
ARTICLE (pdf)  Abstract, Citation & References  Citations: 2  PubMed
Country of the authors Japan and USA   
Corresp. author's affiliation: Prof. William A. Boisvert, Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
Funding grants from NIH (R01HL075677 and R01HL081863 to WAB) and from the Japanese Ministry of Health, Labor and Welfare, Tokyo, Japan (to NK)

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Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro

Ndishabandi D, Duquette C, Billah GE, Reyes M, Duquette M, Lawler J, Kazerounian S. Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro. Discoveries 2014, Oct-Dec; 2(4): e31. DOI: 10.15190/d.2014.23
ARTICLE (pdf)  Abstract, Citation & References  Citations: 3  PubMed
Country of the authors USA
Corresp. author's affiliation: Prof. Kazerounian, PhD - Department of Pediatrics, Division of Genetics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Funding NCI grant CA130895 (to JL) and institutional training grant T32 HL07893 (to KS)

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The role of mutations at codons 32, 47, 54, and 90 in HIV-1 protease flap dynamics

Chordia P, Dewdney TG, Keusch B, Kuiper BD, Ross K, Kovari IA, MacArthur R, Salimnia H, Kovari LC. The role of mutations at codons 32, 47, 54, and 90 in HIV-1 protease flap dynamics. Discoveries 2014, Oct-Dec; 2(4): e27. DOI: 10.15190/d.2014.19
ARTICLE (pdf)  Abstract, Citation & References  Citations: 2
Country of the authors USA
Corresp. author's affiliation: Prof. Kovari, PhDDepartment of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, MI, USA.
Funding NIH grant to LCK (AI65294) and IMSD/MBRS fellowship support to TGD

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Characterization of rapid neutrophil extracellular trap formation and its cooperation with phagocytosis in human neutrophils
Saffarzadeh M, Cabrera-Fuentes HA, Veit F, Jiang D, Scharffetter-Kochanek K, Gille C, Rooijakkers SHM, Hartl D, Preissner KT. Characterization of rapid neutrophil extracellular trap formation and its cooperation with phagocytosis in human neutrophils. Discoveries  2014, Apr-Jun; 2(2): e19. DOI: 10.15190/d.2014.11
Country of the authors Germany and Netherlands
Corresp. author's affiliation: Prof. Preissner, PhDJustus-Liebig-University, Giessen, Germany & University Medical Center Mainz, Mainz, Germany;
Funding start-up grant from the Excellence-Cluster Cardio-Pulmonary System (German Research Foundation) to MS, by the German Federal State of Hesse (LOEWE Research Network ‘Insect Biotechnology’) as well as by the Transregional Collaborative Research Center SFBTR84 (German Research Foundation) to KTP

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PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor

Bucur O, Stancu AL, Muraru MS, Melet A, Petrescu SM, Khosravi-Far R. PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor. Discoveries  2014, Apr-Jun; 2(2): e16. DOI: 10.15190/d.2014.8
ARTICLE (pdf)  Suppl. Material (pdf)  Abstract, Citation & References  Citations: 4  PubMed
Country of the authors USA, Romania and France
Corresp. author's affiliation: Dr. Octavian Bucur, MD, PhDBIDMC & Harvard Medical School, Boston, MA, USA
Funding NIH grants CA105306, CA131664, HL080192 to RKF and Lady Tata Memorial Trust, London, UK to OB

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White noise and neuronal porosome complex: transmission electron microscopic study

Zhvania MG, Bikashvili TZ, Japaridze NJ, Lazrishvili II, Ksovreli M. White noise and neuronal porosome complex: transmission electron microscopic study. Discoveries 2014, Jul-Sep; 2(3): e25. DOI: 10.15190/d.2014.17
ARTICLE (pdf)  Abstract, Citation & References  Citations: 4
Country of the authors Georgia
Corresp. author's affiliation: Prof. Zhvania, PhDHead, Laboratory of Neuron Ultrastructure and Nanoarchitecture, I. Beritashvili Center of Experimental Biomedicine & Ilia State University, Tbilisi, Georgia
Funding Georgian Academy of Science and I. Beritashvili Center of Experimental Biomedicine

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Insights into the Nanobiology of Growth Hormone Secretion

Anderson LL. Insights into the Nanobiology of Growth Hormone Secretion. Discoveries 2014, Jul-Sep; 2(3): e22. DOI: 10.15190/d.2014.14
ARTICLE (pdf)  Abstract, Citation & References  Citations: 1
Country of the authors USA  
Corresp. author's affiliation: Prof. Anderson, PhD - Emeritus Professor of Animal Science, Charless F. Curtiss Distinguished Professor in Agriculture and Life Sciences, Iowa State University, Ames, IA, USA
Funding US Department of Agriculture, National Research Initiative Grants by USDA NRI 2003-35206-12817 and 2005-3560415618, the Iowa Agriculture and Home Economics Experiment Station, Ames,Iowa and by Hatch Act and State of Iowa funds (to LLA) 

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Data integration of 104 studies related with microRNA epigenetics revealed that miR-34 gene family is silenced by DNA methylation in the highest number of cancer types
Ziga Strmsek, Tanja Kunej. Data integration of 104 studies related with microRNA epigenetics revealed that miR-34 gene family is silenced by DNA methylation in the highest number of cancer types.  Discoveries  2014, Apr-Jun; 2(2): e18. DOI: 10.15190/d.2014.10
Country of the authors Slovenia
Corresp. author's affiliation: Prof. Tanja Kunej, PhD - Chair of Genetics, Animal Biotechnology and Immunology, University of Ljubljana, Slovenia
Funding Slovenian Research Agency (ARRS) through the Research programme Comparative genomics and genome biodiversity (P4-0220; to TK)

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Novel insights into the mechanism of cell-based therapy after chronic myocardial infarction
Schuh A, Butzbach B, Curaj A, Simsekyilmaz S, Bucur O, Kanzler I, Denecke B, Konschalla S, Kroh A, Sönmez TT, Marx N, Liehn EA.  Novel insights into the mechanism of cell-based therapy after chronic myocardial infarction. Discoveries 2014, Jan-Mar; 2(1): e9. DOI: 10.15190/d.2014.1  
ARTICLE (pdf)  Abstract, Citation & References  Citations: 5
Country of the authors Germany, Romania and USA
Corresp. author's affiliation: Prof. Liehn, MD, PhD - IMCAR, RWTH Aachen University, Germany

FundingDeutsche Forschungsgemeinschaft (Forschergruppe 809) and the Interdisciplinary Centre for Clinical Research IZKF Aachen within the faculty of Medicine at RWTH Aachen University



REVIEW Articles

A CRISPR View of Biological Mechanisms

Martinez E, Sanchez L, Vazquez N, Marks R, Cedillo R, Respondek C, Holguin M, Persans M, Keniry M. A CRISPR View of Biological Mechanisms. Discoveries 2016, Oct-Dec; 4(4): e69. DOI: 10.15190/d.2016.16
Country of the authors TX, USA
Corresp. authors' affiliation: Prof. Megan Keniry, PhD, Department of Biology, University of Texas Rio Grande Valley, 1201 W. University Dr., Edinburg, TX 78539
Funding: US Department of Agriculture. M.K., E.M. and M.W.P. grants: 2016-38422-25760 and 2015-38422-24061, the National Science Foundation: M.K. grants: 1463991 and 1209210, and the UTRGV College of Sciences Seed Grant 

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Acquisition, Visualization and Potential Applications of 3D Data in Anatomic Pathology

Prajapati S, Madrigal E, Friedman MT. Acquisition, Visualization and Potential Applications of 3D Data in Anatomic Pathology. Discoveries 2016, Oct-Dec; 4(4): e68. DOI: 10.15190/d.2016.15
Country of the authors NY, USA
Corresp. authors' affiliation: Dr. Shyam Prajapati, DO, Mount Sinai West, Diagnostic Pathology & Laboratory Medicine, 1000 Tenth Ave, New York, NY, 10019, USA
Funding: Mount Sinai Health System, the Department of Diagnostic Pathology and Laboratory

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Bacterial RNA as a signal to eukaryotic cells as part of the infection process

Simonov D, Swift S, Blenkiron C, Phillips AR. Bacterial RNA as a signal to eukaryotic cells as part of the infection process. Discoveries 2016, Oct-Dec; 4(4): e70. DOI: 10.15190/d.2016.17
Country of the authors New Zealand
Corresp. authors' affiliationSimon Swift, PhD, Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
FundingLottery Health Research (New Zealand (NZ)), Health Research Council (NZ), Maurice Wilkins Centre for Biodiscovery (NZ), Maurice and Phyllis Paykel Trust (NZ), Ministry of Business, Innovation and Employment (NZ), Johnson and Johnson Surgical Research Fellowship (NZ).

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Quantitative dynamics of VE-cadherin at endothelial cell junctions at a glance: basic requirements and current concepts

Seebach J, Cao J, Schnittler HJ. Quantitative dynamics of VE-cadherin at endothelial cell junctions at a glance: basic requirements and current concepts. Discoveries 2016, Jul-Sep; 4(3): e63. DOI: 10.15190/d.2016.10
Country of the authors Germany
Corresp. authors' affiliationProf. Hans Joachim Schnittler, MD, Managing Director, Institute of Anatomy and Vascular Biology, Vesaliusweg 2-448149 Münster, Germany
FundingGerman Research Council (DFG INST 2105/24–1 and SCHN 430/6–2) the Excellence Cluster Cells In Motion (CIM), and WWU-Münster flexible fund to H.S (FF-2016-15)

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The mechanisms, diagnosis and management of mitral regurgitation in mitral valve prolapse and hypertrophic cardiomyopathy

Popa MO, Irimia AM, Papagheorghe MN, Vasile EM, Tircol SA, Negulescu RA et al. The mechanisms, diagnosis and management of mitral regurgitation in mitral valve prolapse and hypertrophic cardiomyopathy. Discoveries 2016, Apr-Jun; 4(2): e61. DOI: 10.15190/d.2016.8
Country of the authors Romania
Corresp. authors' affiliation: Dr. Mihaela Octavia Popa, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
Funding: support from Carol Davila University of Medicine and Pharmacy, Monza and Floreasca Clinical Emergency Hospitals

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The Biological Functions of Non-coding RNAs: From a Line to a Circle
Wu N, Yang BB. The Biological Functions of Non-coding RNAs: From a Line to a Circle. Discoveries 2015, Jul-Sep; 3(3): e48. DOI: 10.15190/d.2015.40
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors Canada
Corresp. author's affiliation: Prof. Yang, PhD, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Funding: Discovery Grant from the National Sciences and Engineering Research Council of Canada (NSERC; 227937-2012) to BBY who is the recipient of a Career Investigator Award (CI 7418) from the Heart and Stroke Foundation of Ontario

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NF-κB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures

Singh V, Gupta D, Arora R. NF-κB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures. Discoveries 2015, Jan-Mar; 3(1): e35. DOI: 10.15190/d.2015.27
Corresp. author's affiliation: Prof. Gupta, PhD Division of Radiation Biosciences, Institute of Nuclear Medicine & Allied Sciences, Defence Research and Development Organisation, Delhi, India
Funding: grant from UCG (University Grants Commission) of India, a statutory body set up by the Indian Union government (to DG)

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Inflammation markers in cutaneous melanoma - edgy biomarkers for prognosis

Neagu M, Constantin C, Dumitrascu GR, Lupu AR, Caruntu C, Boda D, Zurac S. Inflammation markers in cutaneous melanoma - edgy biomarkers for prognosis. Discoveries 2015, Jan-Mar; 3(1): e38. DOI: 10.15190/d.2015.30
ARTICLE (pdf)  Abstract, Citation & References  Citations: 6
Country of the authors Romania  
Corresp. author's affiliation: Prof. Neagu, MD, PhD, Head of Immunobiology, "Victor Babes" National Institute of Pathology, Romania
Funding: grant from Romanian Ministry of Education and Research, UEFISCDI research project PN - II - PCCA - 2013 - 4 – 1407 (acronym MELTAG, grant no. 190/2014) and PN 09.33 - 01.01

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Porosome in Cystic Fibrosis

Jena B. Porosome in Cystic Fibrosis. Discoveries 2014, Jul-Sep; 2(3): e24. DOI: 10.15190/d.2014.16
ARTICLE (pdf)  Abstract, Citation & References  Citations: 1
Country of the authors USA
Corresp. author's affiliation: Prof. Jena, Ph.D., D.Sc., (dr. h.c. mult.), George E. Palade University Professor, Distinguished Professor, Department of Physiology, Wayne State University School of Medicine; Director of the NanoBioScience Institute, Detroit, MI, USA 
Funding: NIH grant R01EB000303 (to BPJ)

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Porosome: a membrane microdomain acting as the universal secretory portal in exocytosis

Leabu M, Niculite CM. Porosome: a membrane microdomain acting as the universal secretory portal in exocytosis. Discoveries 2014, Jul-Sep; 2(3): e29. DOI: 10.15190/d.2014.21 
ARTICLE (pdf)  Abstract, Citation & References  Citations: 4
Country of the authors Romania
Corresp. author's affiliation: Prof. Leabu, PhDHead of Cell Biology Laboratory, "Victor Babes" National Institute, and Associate Professor, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
Funding: Romanian Ministry of Education, grant PN.09. 33.0205

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Quantal Basis of Secretory Granule Biogenesis and Inventory Maintenance: the Surreptitious Nano-machine Behind It

Hammel I and Meilijson I. Quantal Basis of Secretory Granule Biogenesis and Inventory Maintenance: the Surreptitious Nano-machine Behind It. Discoveries 2014, Jul-Sep; 2(3): e21. DOI: 10.15190/d.2014.13 
ARTICLE (pdf)  Suppl. Material (pdf)  Abstract, Citation & References  Citations: 4
Country of the authors Israel
Corresp. author's affiliation:  Prof. Hammel, PhD - Head of the Faculty Graduate School, Department of Pathology, Tel Aviv University & Prof. Meilijson, PhD - Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel
Funding: Tel Aviv University Intramural Research Program Funds

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Porosome in the Exocrine Pancreas: A Detailed EM Study

Craciun C. Porosome in the Exocrine Pancreas: A Detailed EM Study. Discoveries 2014, Jul-Sep; 2(3): e23. DOI: 10.15190/d.2014.15 
ARTICLE (pdf)  Suppl. Material (pdf)  Abstract, Citation & References  Citations: 1
Country of the authors Romania
Corresp. author's affiliation: Prof. Craciun, PhD - Director, Center of Electron Microscopy, Babes-Bolyai University, Cluj-Napoca, Romania

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Blood Transfusion in the 21st Century

Friedman MT, Avadhani V, Gilmore S, Madrigal E. Blood Transfusion in the 21st Century. Discoveries 2014, Jan-Mar; 2(1): e11. DOI: 10.15190/d.2014.3 
ARTICLE (pdf)   Abstract & References   Citations: 2
Country of the authors USA
Corresp. author's affiliation: Prof. Friedman, MD - St. Luke’s, Roosevelt, and Beth Israel Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY, USA 

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DNA bending in the synaptic complex in V(D)J recombination: turning an ancestral transpososome upside down

Ciubotaru M, Surleac M, Mihaela G. Musat MG, Rusu AM, Ionita E, Albu PCC. DNA bending in the synaptic complex in V(D)J recombination; turning an ancestral transpososome upside down. Discoveries 2014, Jan-Mar; 2(1): e13. DOI: 10.15190/d.2014.5 
ARTICLE (pdf)   Abstract & References   Citations: 0
Country of the authors USA and Romania
Corresp. author's affiliation: Prof. Ciubotaru, MD, PhDYale University School of Medicine, New Haven, CT, USA
Funding: Romanian Ministry of Education and Research, Agentia Nationala pentru Cercetarea Stiintifica (ANCS grant PN-II-IDPCCE-2011-2-0024 to M.C, M.G.M, A.M.R, E. I and P.C.C.A) and the Romanian Academy (ANCS grant ID 3-0342-181/2011 M.S.)

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Update of the 1972 Singer-Nicolson Fluid—Mosaic Model of Membrane Structure

Nicolson GL.  Update of the 1972 Singer-Nicolson Fluid-Mosaic Model of Membrane Structure. Discoveries 2013, Oct-Dec; 1(1): e3. DOI: 10.15190/d.2013.3
Country of the authors USA
Corresp. author's affiliation: Prof. Nicolson, PhD - Director, Institute for Molecular Medicine, Huntington Beach, CA, USA
Funding: Institute for Molecular Medicine

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Critical physiological and pathological functions of Forkhead Box O tumor suppressors

Dumitrascu GR, Bucur O.  Critical physiological and pathological functions of Forkhead Box O tumor suppressors. Discoveries 2013, Oct-Dec; 1(1): e5. DOI: 10.15190/d.2013.5
Country of the authors Romania and USA
Corresp. author's affiliation: Dr. Bucur, MD, PhDHarvard Medical School and BIDMC, Boston, MA, USA

Funding: Research Project PN 09.33 - 01.01 (GRD), Romanian Ministry of Education and Research



FOCUSED REVIEWS and PERSPECTIVE Articles

Simple Chemoinformatics Criterion Using Electron Donor-Acceptor Molecular Characteristics for Selection of Antibiotics Against Multi-Drug-Resistant Bacteria

Veljkovic V, Glisic S, Perovic V, Paessler S, Veljkovic N, Nicolson GL. Simple Chemoinformatics Criterion Using Electron Donor-Acceptor Molecular Characteristics for Selection of Antibiotics Against Multi-Drug-Resistant Bacteria. Discoveries 2016, Jul-Sep; 4(3): e64. DOI: 10.15190/d.2016.11
Country of the authors Serbia and USA
Corresp. authors' affiliation: Prof. Garth L. Nicolson, PhD, MD (H), Department of Molecular Pathology, The Institute for Molecular Medicine, Huntington Beach, CA, 92647, USA
Funding: Ministry of Education and Science of the Republic of Serbia (Grant no. 173001) 

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Of Kindlins and Cancer

Plow EF, Das M, Bialkowska K, Sossey-Alaoui K. Of Kindlins and Cancer. Discoveries 2016, Apr-Jun; 4(2): e59. DOI: 10.15190/d.2016.6

Country of the authors USA
Corresp. authors' affiliationProf. Edward Plow, PhDThe Robert C. Tarazi, MD, Endowed Chair in Heart and Hypertension Research, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
Funding: NIH grants HL096062 and HL073311 (to EFP) 

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Erythrocyte membrane in type 2 diabetes mellitus

Gabreanu GR, Angelescu S. Erythrocyte membrane in type 2 diabetes mellitus. Discoveries 2016, Apr-Jun; 4(2): e60. DOI: 10.15190/d.2016.7
Country of the authors Romania
Corresp. authors' affiliation: Prof. Silvana Angelescu, MD, Hemathology Department, Coltea Clinical Hospital, Bucharest, Romania
Funding: framework of Medical Residency Programme of GRG, under SA's supervision, Hematology Department, Coltea Clinical Hospital, Bucharest 

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A Versatile Gene Delivery System for Efficient and Tumor Specific Gene Manipulation in vivo

Wang W, Dong B, Ittmann MM, Yang F. A Versatile Gene Delivery System for Efficient and Tumor Specific Gene Manipulation in vivo. Discoveries 2016, April-June; 4(2): e58. DOI: 10.15190/d.2016.5
Country of the authors:  USA
Corresp. authors' affiliation: Prof. Feng Yang, Ph.D., Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, 77030, USA
Funding:  NIH (U01 CA141497 to MMI), US Department of Defense Congressionally Directed Medical Research Programs (W81XWH-09-1-0618, W81XWH-09-1-0651, W81XWH-13-1-0162, W81XWH-13-1-0163 to FY), , and the Cancer Prevention and Research Institute of Texas (RP130651 to FY) 

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Clinical Uses of Membrane Lipid Replacement Supplements in Restoring Membrane Function and Reducing Fatigue in Chronic Diseases and Cancer

Nicolson GL, Rosenblatt S, Ferreira de Mattos G, Settineri R, Breeding PC, Ellithorpe RR and Ash ME. Clinical Uses of Membrane Lipid Replacement Supplements in Restoring Membrane Function and Reducing Fatigue in Chronic Diseases and Cancer. Discoveries 2016, Jan-Mar; 4(1): e54. DOI: 10.15190/d.2016.1
Country of the authors USA, Uruguay and UK
ARTICLE (pdf)  Abstract, Citation & References  Citations: 3 
Corresp. author's affiliation: Prof. Emeritus Garth L. Nicolson, PhD, MD (H), Department of Molecular Pathology, The Institute for Molecular Medicine, P.O. Box 9355, S. Laguna Beach, CA 92652, USA
Funding: grants and contracts to the Institute for Molecular Medicine.

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microRNA regulators of apoptosis in cancer

Bucur O. microRNA regulators of apoptosis in cancer. Discoveries 2016, Jan-Mar; 4(1): e57. DOI: 10.15190/d.2016.4
Country of the authors USA
Corresp. authors' affiliation: *Dr. Bucur, MD, PhD, Department of Pathology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA
Funding: Lady TATA Memorial Trust Fellowship (London, UK) 

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AMPK activation can delay aging

Stancu AL. AMPK activation can delay aging. Discoveries 2015, Oct-Dec; 3(4): e53. DOI: 10.15190/d.2015.45
ARTICLE (pdf)  Abstract, Citation & References
Country of the authors USA
Corresp. author's affiliation: Dr. Stancu, MD, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA..
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Emerging technologies for diagnostic pathology

Bucur O. Emerging technologies for diagnostic pathology. Discoveries 2015, Apr-Jun; 3(2): e46. DOI: 10.15190/d.2015.38
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors USA   
Corresp. author's affiliation: Dr. Bucur, MD, PhDCancer Research Institute, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
Funding: Lady TATA Memorial Trust Fellowship (London, UK) .

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Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts

Frangogiannis NG. Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts. Discoveries 2015, Jan-Mar; 3(1): e41. DOI: 10.15190/d.2015.33
ARTICLE (pdf)  Abstract, Citation & References  Citations: 9  PubMed
Country of the authors USA 
Corresp. author's affiliation: Prof. Frangogiannis, MD, PhD, Chair in Cardiovascular Medicine, The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, NY, USA
Funding: NIH grants R01 HL76246 and R01 HL85440 (to NGF)

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Life style, Perfusion deficits and Co-morbidities Precipitate Inflammation and Cerebrovascular Disorders in Aged Subjects

Uzoni A, Ciobanu O, Sandu RE, Buga AM, Popa-Wagner A. Life style, Perfusion deficits and Co-morbidities Precipitate Inflammation and Cerebrovascular Disorders in Aged Subjects. Discoveries 2015, Jan-Mar; 3(1): e39. DOI: 10.15190/d.2015.31
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors Germany and Romania 
Corresp. author's affiliation: Prof. Popa-Wagner, PhD, Head of the Research Molecular Psychiatry, Department of Psychiatry, University of Medicine Rostock, Germany
Funding: grants from the European Social Found, Human Resources Development Operational Programme 2007-2013, project no. POSDRU/159/1.5/S/136893 (to RES), Romanian National Authority for Scientific Research, CNCSUEFISCDI, project number PN-II-PT-PCCA-2011-3, No 80/2012 (to APW)

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Key principles of miRNA involvement in human diseases

Giza DE, Vasilescu C, Calin GA. Key principles of miRNA involvement in human diseases. Discoveries 2014, Oct-Dec; 2(4): e34. DOI: 10.15190/d.2014.26
ARTICLE (pdf)  Abstract, Citation & References  Citations: 8  PubMed
Country of the authors USA and Romania  
Corresp. author's affiliation: Prof. Calin, MD, PhD - Co-Director of the Center for RNA Interference and Non-Coding RNAs, Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, TX, USA
Funding: Dr Calin is The Alan M. Gewirtz Leukemia & Lymphoma Society Scholar. Work in Dr. Calin’s laboratory is supported in part by the NIH/NCI grants 1UH2TR00943-01 and 1 R01 CA182905-01, Developmental Research Awards in Prostate Cancer, Multiple Myeloma, Leukemia (P50 CA100632), Head and Neck (P50 CA097007) and Brain (2P50CA127001) SPOREs, a SINF MDACC_DKFZ grant in CLL, a SINF grant in colon cancer, and a Kidney Cancer Pilot Project. The Center for Cancer Epigenetics Pilot project, a 2014 Knowledge GAP MDACC grant, the Laura and John Arnold Foundation, the RGK Foundation and the Estate of C. G. Johnson, Jr and by the CLL Global Research Foundation. This work was also supported also by a grant from The University of Texas MD Anderson Cancer Center Duncan Family Institute for Cancer Prevention and Risk Assessment. Dr.Dana Elena Giza was funded in part by CNCSUEFISCDI project PN-IIID-PCE-2012-4-0018 and by the Romanian National Research Council (CNCS) Complex Exploratory Research Projects (Grant CEEX 187/2006).

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New perspective in heart failure management: could myosin activators be the answer?

Andrei S, Iorgoveanu C. New perspective in heart failure management: could myosin activators be the answer? Discoveries 2014, Oct-Dec; 2(4): e33. DOI: 10.15190/d.2014.25
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors France and Romania  
Corresp. author's affiliation: Dr. Andrei, MD - CNHO des Quinze-Vingts, Service de Médecine Interne, Paris, France

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Exosomes: Emerging Players of Intercellular Communication in Tumor Microenvironment

Maheshwari S, Singh AK, Arya RK, Pandey D, Singh A, Datta D. Exosomes: Emerging Players of Intercellular Communication in Tumor Microenvironment. Discoveries 2014, Jul-Sep; 2(3): e26. DOI: 10.15190/d.2014.18
ARTICLE (pdf)  Abstract, Citation & References  Citations: 6
Country of the authors India

Corresp. author's affiliation: Prof. Datta, PhD - CSIR-Central Drug Research Institute (CDRI), Lucknow, India & Academy of Scientific and Innovative Research, New Delhi, India

Funding: several network projects and fellowships grants from Indiand Council of Scientific and Industrial Research (CSIR), Indian University Grants Commission (UGC) and Ministry of Earth Science (MOES)

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New Frontiers for the NFIL3 bZIP Transcription Factor in Cancer, Metabolism and Beyond

Megan Keniry, Robert K. Dearth, Michael Persans, and Ramon Parsons. New Frontiers for the NFIL3 bZIP Transcription Factor in Cancer, Metabolism and Beyond. Discoveries  2014, Apr-Jun; 2(2): e15. DOI: 10.15190/d.2014.7
ARTICLE (pdf)  Abstract, Citation & References  Citations: 3  PubMed
Country of the authors USA
Corresp. author's affiliation: Prof. Keniry, PhD - University of Texas-Pan American, Edinburg, TX, USA &
Prof Parsons, MD, PhD - Chair of Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Funding: NIH/NCI R01 CA082783 (RP)

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Present and Future Applications of High Resolution Mass Spectrometry in the Clinic

Crutchfield CA, Clarke W. Present and Future Applications of High Resolution Mass Spectrometry in the Clinic. Discoveries  2014, Apr-Jun; 2(2): e17. DOI: 10.15190/d.2014.9
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors USA
Corresp. author's affiliation: Prof. Clarke, PhD - Director of Clinical Toxicology and Point-of-Care Testing, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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New agents for the treatment of lymphoid leukemia and lymphoma: Focus on Recent FDA Approvals
Stancu AL, Smith MR, Almasan A. New agents for the treatment of lymphoid leukemia and lymphoma: focus on recent FDA approvals. Discoveries 2014, Jan-Mar; 2(1): e14. DOI: 10.15190/d.2014.6 
ARTICLE (pdf)  Abstract & References  Citations: 1  PubMed
Country of the authors USA
Corresp. author's affiliation: Prof. Almasan, PhD - Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
Funding: NIH grant CA127264 (to AA) 

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Unfolded Protein Response and Cancer

Wu L, Chou M, Zhu S. Unfolded Protein Response and Cancer. Discoveries 2014, Jan-Mar; 2(1): e10. DOI: 10.15190/d.2014.2 
ARTICLE (pdf)  Abstract & References  Citations: 0
Country of the authors China and Canada
Corresp. author's affiliation: Prof. Zhu, PhD - Central South University, Changsha, China

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The Bidirectional Relationship between Metabolism and Immune Responses

Raval FM, Nikolajczyk BS.  The Bidirectional Relationship between Metabolism and Immune Responses. Discoveries 2013, Oct-Dec; 1(1): e6. DOI: 10.15190/d.2013.6
Country of the authors USA
Corresp. author's affiliation: Prof. Nikolajczyk, PhD - Boston University School of Medicine, Boston, MA, USA
Funding: NIH grant R56 DK096525 (to BSN)

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The still valid fluid mosaic model for molecular organization of biomembranes: accumulating data confirm it

Leabu M.  The still valid fluid mosaic model for molecular organization of biomembranes: accumulating data confirm it. Discoveries 2013, Oct-Dec; 1(1): e7. DOI: 10.15190/d.2013.7
Country of the authors Romania
Corresp. author's affiliation: Prof. Leabu, PhDCarol Davila University of Medicine and Pharmacy & Victor Babes National Institute of Pathology,  Bucharest, Romania

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Akt modes of stem cell regulation: more than meets the eye?
Calautti E.  Akt modes of stem cell regulation: more than meets the eye? Discoveries 2013, Oct-Dec; 1(1): e8. DOI: 10.15190/d.2013.8
Country of the authors Italy
Corresp. author's affiliation: Prof. Calautti, PhD - University of Turin, Italy
Funding: Telethon Foundation (TCP 06001), the Piedmont Region (PISTEM and Converging Technologies Grants) to EC 


DISCOVERIES IN IMAGES

Nano-level morphology of scar tissue after myocardial infarction

Wu Z, Curaj A, Staudt M, Ponomariov V, Decker L, Rusu M*. Nano-level morphology of scar tissue after myocardial infarction. Discoveries 2015, Jul-Sep; 3(3): e49. DOI: 10.15190/d.2015.41
ARTICLE (pdf)  Abstract, Citation & References  Citations: 0
Country of the authors Germany    
Corresp. author's affiliation: * Institute for Molecular Cardiovascular Research, University Hospital Aachen, Germany
Funding: from Interdisciplinary Centre for Clinical Research IZKF Aachen (to EAL) within the faculty of Medicine at RWTH Aachen University.


EDITORIALS (these are PEER-REVIEWED editorials; the non-peer reviewed manuscripts were not included)

Fusion Pore: A Curious Case of Rediscovering Science

Nodar P. Mitagvaria. Fusion Pore: A Curious Case of Rediscovering Science. Discoveries 2017, 5(2): e73 DOI: 10.15190/d.2017.3
Country of the authors Georgia  
Corresp. authors' affiliation:
Prof. Nodar P. Mitagvaria, PhD, ScD, Head, Department of Cerebral Circulation & Metabolism, I. Beritashvili Center of Experimental Biomedicine, 14 Gotua Street, 0162 Tbilisi, Georgia

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An updated h-index measures both the primary and total scientific output of a researcher

Bucur O*, Almasan A*, Zubarev R, Friedman M, Nicolson GL, Sumazin P, Leabu M, Nikolajczyk BS, Avram D, Kunej T, Calin GA, Godwin AK, Adami H, Zaphiropoulos PG, Richardson DR, Schmitt-Ulms G, Westerblad H, Keniry M, Grau GER, Carbonetto S, Stan RV, Popa-Wagner A, Takhar K, Baron BW, Galardy PJ, Yang F, Data D, Fadare O, Yeo KJ, Gabreanu GR, Andrei S, Soare GR, Nelson MA, Liehn EA*. An updated h-index measures both the primary and total scientific output of a researcher. Discoveries 2015, Jul-Sep; 3(3): e50.
Country of the authors USA, Sweden, Romania, Australia, Canada, France and Germany 
Corresp. author's affiliation: *Harvard Medical School, Boston, USA, Cleveland Clinic, OH, USA & University Hospital Aachen, Germany
Funding: Dr. Alexandru Almasan is funded by the NCI grant RO1 CA184137-01. Dr. Bucur was supported by the Lady Tata Memorial Trust Award, London, UK. Dr. Tanja Kunej is supported by the Slovenian Research Agency (ARRS) through the Research programme (P4-0220). Dr. George Calin is The Alan M. Gewirtz Leukemia & Lymphoma Society Scholar. Work in Dr. George Calin’s laboratory is supported in part by the NIH/NCI grants 1UH2TR00943-01 and 1 R01 CA182905-01, the UT MD Anderson Cancer Center SPORE in Melanoma grant from NCI (P50 CA093459), Aim at Melanoma Foundation and the Miriam and Jim Mulva research funds, the Brain SPORE (2P50CA127001), the Center for Radiation Oncology Research Project, the Center for Cancer Epigenetics Pilot project, a 2014 Knowledge GAP MDACC grant, a CLL Moonshot pilot project, the UT MD Anderson Cancer Center Duncan Family Institute for Cancer Prevention and Risk Assessment, a SINF grant in colon cancer, the Laura and John Arnold Foundation, the RGK Foundation and the Estate of C. G. Johnson, Jr.  Dr. Andrew K. Godwin is the Chancellor’s Distinguished Chair in Biomedical Sciences Endowed Professor and a Kansas Bioscience Authority Eminent Scholar.  Work in Dr. Godwin’s program is supported in part by the NCI (R21CA186846, R01CA106588, R01CA140323, R01CA140323-S1, U01CA113916, & P30CA168524), the NIH (UL1TR000001), the Braden's Hope Foundation, the Vicki Welsh Fund, and the OVERRUN Ovarian Cancer Foundation. Dr. Des Richardson is funded by the National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowship and Project Grants. Peter G. Zaphiropoulos is supported by the Swedish Childhood Cancer Foundation (PROJ12/032) and the AFA Insurance (Dnr: 130014). Dr. Håkan Westerblad is funded by the Swedish Research Council and Swedish National Center for Sports Research. Dr. Radu V. Stan is funded by the NIH CA172983 (PI: Stan), CA023108 (PI: Israel) grants. Takhar Kasumov is supported by the NIH/NIGM (1RO1 GM112044-01A1), NIH/NHBLI (1R21 HL114407-01A1) grants. Georgiana R. Gabreanu  is funded by the Research Project: PN 09.33 - 01.01. Dorina Avram is funded by the NIH (R01 AI067846, R21 AI112492). Gerold Schmitt-Ulms is funded by the Canadian Institutes for Health Research (CIHR). Paul J. Galardy is supported by the National Cancer Institute (CA151351), the Multiple Myeloma Research Foundation, the Gabrielle’s Angel Foundation for Cancer Research, and the Hyundai Hope on Wheels Foundation. Dr. Galardy is a former ASH Basic Research Scholar, a past recipient of the Howard Hughes Medical Institute Physician Scientist Early Career Award, and a former Harriet H. Samuelsson Foundation Pediatric Cancer Research Scientist. Dipak Datta is funded by the CSIR-Central Drug Research Institute Fund. Dr. Elisa A. Liehn is funded by the Interdisciplinary Centre for Clinical Research IZKF Aachen within the Faculty of Medicine at RWTH Aachen University

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Recent Studies on the Insulin-Secreting Porosome Complex Provide Potential Therapeutic Applications in the Treatment of Diabetes

Anderson LL. Recent Studies on the Insulin-Secreting Porosome Complex Provide Potential Therapeutic Applications in the Treatment of Diabetes. Discoveries 2015, Oct-Dec; 3(4): e51. DOI: 10.15190/d.2015.43
Country of the authors USA  
Corresp. authors' affiliation:
Emeritus Professor Anderson LL, PhD, of Animal Science, Charless F. Curtiss Distinguished Professor in Agriculture and Life Sciences, Iowa State University, Ames, IA, USA
Funding US Department of Agriculture, National Research Initiative Grants by USDA NRI 2003-35206-12817 and 2005-3560415618, the Iowa Agriculture and Home Economics Experiment Station, Ames,Iowa and by Hatch Act and State of Iowa funds (to LLA)

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Initiative for standardization of the format of the next-generation sequencing (NGS) results

Pipan V, Kunej T. Initiative for standardization of the format of the next-generation sequencing (NGS) results. Discoveries 2015, Apr-Jun; 3(2): e44. DOI: 10.15190/d.2015.36
Country of the authors Slovenia 
Corresp. authors' affiliation:
Prof. Kunej, PhDChair of Genetics, Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Slovenia
Funding Slovenian Research Agency (ARRS) through the Research programme Comparative genomics and genome biodiversity (P4-0220; to TK)

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Inflammation between defense and disease: impact on tissue repair and chronic sickness

Liehn EA, Cabrera-Fuentes HA. Inflammation between defense and disease: impact on tissue repair and chronic sickness. Discoveries 2015, Jan-Mar, 3(1): e42. DOI: 10.15190/d.2015.34
Country of the authors Germany and Singapore 
Corresp. authors' affiliation:
Prof. Liehn, MD, PhD, Institute of Molecular Cardiovascular Research, RWTA Aachen, Aachen, Germany
Dr. Cabrera-Fuentes, Ph.D, Institute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany
Funding IZKF founding RWTH Aachen to EAL

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Cell secretion and membrane fusion: highly significant phenomena in the life of a cell

Leabu M, Nicolson GL. Cell secretion and membrane fusion: highly significant phenomena in the life of a cell. Discoveries 2014, Jul-Sep; 2(3): e30. DOI: 10.15190/d.2014.22
ARTICLE (pdf)  Citation & References  Citations: 0
Country of the authors Romania and USA  
Corresp. authors' affiliation:
Prof. Leabu, PhD Head of Cell Biology Laboratory, "Victor Babes" National Institute and Associate Professor, "CAROL DAVILA" University of Medicine and Pharmacy, Bucharest, Romania
Prof. Emeritus Nicolson, President and Founder of the Institute for Molecular Medicine, CA, USA, formally David Bruton Jr. Chair in Cancer Research and Chairman of the Department of Tumor Biology at University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA
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News & Events Latest news from Discoveries

  • March 2017 | PubMed inclusion News!

    Discoveries successfully passed the Scientific Quality Review by NLM-NIH for PubMedCentral and PubMed indexing (March 2017). This is the first and the most important step towards PubMedCentral and PubMed indexing! The second (last) step is the Technical Review, which should be faster and without problems.

  • April 2016 | Faster Peer-Review

    Starting on April 13th 2016, all articles selected for a peer-review will receive the post peer-review decision within 10 days. The initial pre-screening time will remain the same (48h from the submission of the manuscript). This decision will significantly accelerate the publication, with no effect on the quality of the peer-review process.

  • February 2016 | Manuscript submission

    Discoveries is commited to excellence, quality and high editorial standards. We are receiving an increasing number of manuscripts for which the identity of the authors/corresponding author can't be verified. Please NOTE that ALL these articles were and will be immediately REJECTED. Indicating an institutional email address is the easiest way to overcome this problem! Moreover, we do not accept any pressure on our editorial board to accept a manuscript. This results in a prompt rejection of the article.

    Editorial Policies
  • January 2016 | Main Objective

    After reaching all proposed milestones until now (including being indexed by Google Scholar in 2014), Discoveries' next Aim is PubMed indexing of all its articles (already published and upcoming). There will be no charge for the submission or publication of articles before Discoveries is indexed.

  • August 2015 | Discoveries - on PubMed

    We are happy to announce that our first Discoveries articles were included in PMC and PubMed. More articles (submitted by NIH funded authors) are now processed for being included.

    Discoveries articles now on PubMed
  • April 2015 | Special Issue

    DISCOVERIES published the SPECIAL ISSUE entitled "INFLAMMATION BETWEEN DEFENSE AND DISEASE: Impact on Tissue Repair and Chronic Sickness".

    Special Issue on "Inflammation"
  • 2015 | Ischemia Collection

    DISCOVERIES launched a call for papers for a Collection of Articles with focus on "ISCHEMIA". If you are interested to submit a manuscript, please contact us at info@discoveriesjournals.org

  • September 2014 | Special Issue

    DISCOVERIES just publish the SPECIAL ISSUE entitled "CELL SECRETION & MEMBRANE FUSION" in September 2014. Initially scheduled for publication between October 2014-March 2015, this issue was successfully published earlier than scheduled. 

    Special Issue
  • April 2014 | Indexed by Google Scholar

    All our published articles are now indexed by Google Scholar! First citations to Discoveries articles are included! Search for the article's title (recommended) or the authors:

    Google Scholar Search
  • 2014 | DISCOVERIES

    DOIs (Digital Object Identifiers) are now assigned to all our published manuscripts in Discoveries. DOI uniquely identifies an article and is provided by CrossRef.

    CrossRef
  • July 2013 | Manuscript Submission

    Submit your manuscript FREE, FAST and EASY ! (in less than 1 minute)! There are NO fees for the manuscript submission or publishing of the accepted manuscripts.
    read more

  • July 2013 | DISCOVERIES

    We are now ACCEPTING MANUSCRIPTS for publishing in DISCOVERIES. We aim publishing a small number of high impact experimental articles & reviews (around 40/year) to maintain a high impact factor. Domains of interest: all areas related to Medicine, Biology and Chemistry ...

    read more
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